- Click the Selection tool   and select a region. 
 See Selecting 
 music for some region-selecting shortcuts. and select a region. 
 See Selecting 
 music for some region-selecting shortcuts.
- Press CLEAR 
 (laptop users Fn-6) or select Edit > Clear All Items. Finale erases all music, leaving empty measures behind. 
 (If you want to remove the measures too, double-click until the full measure stack is selected and press the delete key. Pressing the DELETE key without a full  selection erases the music without deleting the measures themselves).